This category provides physician-reviewed information on antipsychotic medications used to manage schizophrenia, bipolar disorder, schizoaffective disorder, and treatment-resistant psychosis. Articles cover first- and second-generation agents, their mechanisms of dopamine and serotonin modulation, therapeutic indications, and evidence-based dosing protocols. Readers will find guidance on monitoring for metabolic syndrome, extrapyramidal symptoms, tardive dyskinesia, and neuroleptic malignant syndrome. Content also addresses drug interactions, adherence strategies, and deprescribing considerations. All material is written to support informed discussions between patients, caregivers, and prescribing clinicians.