Knee pain affects millions of adults annually and can stem from osteoarthritis, ligament tears, meniscal injuries, patellofemoral syndrome, or chronic overuse conditions. Accurate diagnosis typically involves physical examination, imaging studies such as MRI or X-ray, and assessment of joint mobility and inflammatory markers. Treatment protocols range from conservative measures, including targeted physical therapy, NSAIDs, and corticosteroid injections, to surgical interventions like arthroscopy or total knee replacement for severe structural damage. Early intervention reduces the risk of progressive cartilage degradation and long-term functional impairment. Preventive strategies emphasize maintaining healthy body weight, strengthening quadriceps and hamstring muscles, and avoiding repetitive high-impact activities without proper biomechanical support.