Marijuana

Marijuana use disorder affects approximately 9% of regular users, presenting with cognitive impairment, respiratory irritation, and psychological dependence. Chronic consumption alters endocannabinoid receptor signaling, potentially disrupting memory consolidation, executive function, and emotional regulation. Withdrawal manifestations include insomnia, irritability, appetite suppression, and anxiety peaking within the first seven days of cessation. Treatment protocols combine cognitive-behavioral therapy, motivational enhancement strategies, and pharmacological support for comorbid psychiatric conditions. Our medically reviewed articles address dosage interactions, long-term neurological effects, and harm-reduction strategies for both recreational and medicinal users.