The Best Probiotics for Men in 2025

Key takeaways

• Probiotics can support urinary, prostate, and reproductive health in men.
• Probiotic strains aren’t inherently sex-specific, but certain strains may act differently across sexes.
• Culturelle Men’s Daily is our top overall pick for its broad health benefits, CFU amount, and reasonable cost.

A quick look at the best probiotics for men

Probiotics have been shown to aid health in many ways, including supporting digestive wellness, immune function, weight management, and more. For men, probiotics may also help with urinary tract, prostate, and fertility concerns.

Although a product labeled specifically for men isn’t required to obtain most advantages, these formulations sometimes include vitamins and other compounds aimed at male health.

Continue reading to discover what probiotics can offer men and to view our recommended options.

Language matters

Sex and gender exist on spectrums. This article uses the term “men” to refer to a person’s sex assigned at birth.

Our picks of the best probiotics for men

Best for digestive health

Culturelle Men’s Daily Health Probiotics

• Number of servings:30 per container
• Dose:1 capsule per day
• Strains:Lactobacillus rhamnosus GG
• CFU count:10 billion

*Price may vary.

HealthEH’s review

Culturelle, known for a strong women’s probiotic, also offers a once-daily Men’s Daily Health probiotic combined with multivitamins.

We appreciate that this product supplies 10 billion CFUs of Lactobacillus rhamnosus GG, a strain shown to be particularly effective for digestive disorders. It also delivers at least 100% of the recommended daily value of vitamins C, D3, B6, B12, magnesium, and selenium — a nutrient mix that may remove the need for a separate multivitamin.

For men with digestive issues like irritable bowel syndrome (IBS), persistent constipation, or diarrhea, a quality probiotic may be a worthwhile addition. Research indicates probiotic supplements can significantly improve IBS symptoms such as bloating and abdominal discomfort and can help regulate bowel problems like constipation and diarrhea.

Culturelle also promises that their CFU amount remains viable through the expiration date. Because probiotics are live organisms, their viability can be affected by storage duration and temperature. The NIH recommends choosing products that guarantee CFU counts through the end of shelf life rather than only at manufacture, which helps ensure product quality.

Pros & cons

• once-daily capsule
• doesn’t need refrigeration
• affordable

• some users reported no noticeable effects
• some users experienced more frequent bowel movements
• you might still want an extra multivitamin

• once-daily capsule
• doesn’t need refrigeration
• affordable

• some users reported no noticeable effects
• some users experienced more frequent bowel movements
• you might still want an extra multivitamin

Product details

• Form :capsule
• Certifications :none
• Shelf-stable :yes
• Returns :full refund within 30 days
• Shipping :shipping calculated at checkout

• Form :capsule
• Certifications :none
• Shelf-stable :yes
• Returns :full refund within 30 days
• Shipping :shipping calculated at checkout

Best for men over 50

Garden of Life Raw Probiotics Men

• Number of servings:30 per container
• Dose:3 capsules per day
• Strains:Lactobacillus plantarum, Lactobacillus fermentum, Bifidobacterium bifidum, Bifidobacterium lactis, Bifidobacterium longum, Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus casei, Lactobacillus gasseri, Lactobacillus helveticus, Lactobacillus kefiranofaciens, Lactobacillus kefirgranum, Lactococcus lactis, Lactococcus cremoris, Streptococcus thermophilus, Lactobacillus kefir, Lactobacillus parakefir, Lactobacillus brevis, Lactococcus lactis biovar diacetylactis, Leuconostoc lactis, Leuconostoc mesenteroides, Leuconostoc cremoris, Leuconostoc dextranicum, Kluyveromyces marxianus, Brettanomyces anomalus, Debaryomyces hansenii, Saccharomyces unisporus, Saccharomyces turicensis, Saccharomyces cerevisiae, Saccharomyces exiguus, Torulaspora delbrueckii
• CFU count:85 billion

*Price may vary.

HealthEH’s review

For men who want an all-in-one supplement with vitamins, minerals, probiotics, and other supportive ingredients, Garden of Life RAW Men is a strong choice.

This product supplies 85 billion colony-forming units (CFU) from a diverse mix of probiotic strains, including numerous Lactobacillus species, a dominant group in the gut microbiome, plus probiotic yeasts.

Besides the probiotic complex, Garden of Life RAW Men includes key vitamins and minerals important for men’s health, such as B12, vitamin C, vitamin D, selenium, and iodine. Men over 50 are more prone to deficiencies in vitamin B12 and vitamin D, which can negatively affect wellbeing. A combined nutrient supplement can help address dietary shortfalls and support healthy levels.

However, to avoid excessive intake of some nutrients like vitamin E, this product might not be ideal for men already taking a separate multivitamin. Updated findings from the Selenium and Vitamin E Cancer Prevention Trial (SELECT) have linked vitamin E to a higher prostate cancer risk in certain contexts.

Garden of Life guarantees CFU counts through the product’s “best use” date, which is an indicator of higher quality.

Pros & cons

• includes a range of vitamins and minerals
• an all-in-one formulation
• users report digestive benefits

• costly
• needs refrigeration
• requires taking 3 capsules daily

• includes a range of vitamins and minerals
• an all-in-one formulation
• users report digestive benefits

• costly
• needs refrigeration
• requires taking 3 capsules daily

Product details

• Form :capsule
• Certifications :Non-GMO Project Verified
• Shelf-stable :no

• Form :capsule
• Certifications :Non-GMO Project Verified
• Shelf-stable :no

Best for prostate health

Hyperbiotics Pro Men

• Number of servings:30 per container
• Dose:1 tablet per day
• Strains:Lactobacillus fermentum, Probi Lactobacillus plantarum 6595, Lactobacillus acidophilus, Bifidobacterium longum, Lactobacillus casei, Lactobacillus reuteri
• CFU count:5 billion (at manufacture), 1.5 billion (at expiration)

*Price may vary.

HealthEH’s review

Certain probiotics may improve urinary tract and prostate health. Hyperbiotics Pro-Men is clinically shown to reduce bacterial amounts in urine, which could help men who suffer recurrent urinary infections.

The 2021 study of 20 men aged 55–65 with recurrent urinary infections found that daily Hyperbiotics Pro-Men for 12 weeks reduced urinary concentrations of E. coli and E. faecalis—common culprits in urinary infections—compared with placebo.

Research also suggests probiotics can reduce inflammation, which may benefit men with prostatitis. Hyperbiotics Pro-Men includes curcumin, an anti-inflammatory polyphenol shown to help with inflammatory conditions like prostatitis.

All Hyperbiotics ingredients are third-party tested, and the company guarantees at least 1.5 billion viable CFUs at expiration for Pro-Men.

Pros & cons

• no refrigeration needed
• users report digestive improvements
• reasonably priced

• limited number of reviews

• no refrigeration needed
• users report digestive improvements
• reasonably priced

• limited number of reviews

Product details

• Form :tablet
• Shelf-stable :yes
• Returns :returns within 30 days
• Shipping :free shipping on orders over $39

• Form :tablet
• Shelf-stable :yes
• Returns :returns within 30 days
• Shipping :free shipping on orders over $39

Best for weight loss

Jarrow Formulas Jarro-Dophilus EPS Capsules

• Number of servings:60 per container
• Dose:2 capsules per day
• Strains:Lacticaseibacillus rhamnosus, Lactobacillus helveticus, Pediococcus acidilactici, Lacticaseibacillus casei, Bifidobacterium longum, Lactiplantibacillus plantarum, Bifidobacterium breve, Lactococcus lactis subsp. lactis
• CFU count:10 billion

*Price may vary.

HealthEH’s review

Jarro-Dophilus EPS has eight probiotic strains, including some linked to supporting a healthy body weight, such as Bifidobacterium longum. Studies show probiotics with bifidobacteria and lactobacilli may help reduce body fat, waist size, and BMI. A 2019 review also suggests probiotic supplements can improve metabolic markers like blood glucose and insulin resistance.

Researchers propose that high-quality probiotics like Jarro-Dophilus EPS may support weight loss and metabolic health by lowering inflammation, affecting appetite, and improving insulin sensitivity.

The capsules are enteric-coated to help prevent breakdown in the stomach and enhance delivery to the intestines. Jarrow also guarantees CFU counts through the “best used before” date.

Pros & cons

• users report clear digestive benefits
• good value
• no refrigeration required
• available in 120-capsule size
• may require twice-daily dosing

• some doses come in individual packs

• users report clear digestive benefits
• good value
• no refrigeration required
• available in 120-capsule size
• may require twice-daily dosing

• some doses come in individual packs

Product details

• Form :capsule
• Certifications :tested in-house for purity and potency
• Shelf-stable :yes
• Returns :not accepted
• Shipping :calculated at checkout

• Form :capsule
• Certifications :tested in-house for purity and potency
• Shelf-stable :yes
• Returns :not accepted
• Shipping :calculated at checkout

Best vegan probiotic

Mindbodygreen Advanced Probiotic+

• Number of servings:30 servings per container
• Dose:1 capsule per day
• Strains:Lactobacillus acidophilus NCFM, Bifidobacterium lactis Bi-07, Bifidobacterium lactis HN019
• CFU count:22 billion

Use code “HEALTHLINE20” for 20% off.

*Price may vary.

HealthEH’s review

Mindbodygreen Advanced Probiotic+ contains three clinically studied strains to support regular bowel movements and digestion, reduce gas and bloating, and support healthy weight.

The formula includes Lactobacillus acidophilus NCFM, Bifidobacterium lactis Bi-07, and Bifidobacterium lactis HN019.

A 2021 study found that Bifidobacterium lactis HN019 can support gut health by improving bowel function and intestinal motility.

This vegan-friendly supplement is free from dairy, gluten, soy, and GMOs. Mindbodygreen reports the product is third-party tested for purity and potency, although the testing lab isn’t named.

It’s shelf-stable, so refrigeration isn’t needed.

Pros & cons

• vegan, gluten-free, and non-GMO
• no refrigeration required

• higher price
• requires consistent use to see benefits

• vegan, gluten-free, and non-GMO
• no refrigeration required

• higher price
• requires consistent use to see benefits

Product details

• Form :capsule
• Certifications :third-party tested for purity and potency
• Shelf-stable :yes
• Price per serving :$2.67
• Returns :returns within 30 days
• Shipping :free shipping on orders over $98

• Form :capsule
• Certifications :third-party tested for purity and potency
• Shelf-stable :yes
• Price per serving :$2.67
• Returns :returns within 30 days
• Shipping :free shipping on orders over $98

Comparing the best probiotics for men

How we chose the best probiotics for men

Our Medical Standards and Insights team rigorously reviewed and vetted over 11,000 products and services. We fact-checked health assertions, assessed ingredient lists, and evaluated each brand’s reputation before featuring products on HealthEH.

To compile this list, we considered items that passed our vetting criteria and personally tested some to refine our selections.

We chose the best probiotic supplements for men using these factors:

• Vetting: Every product met HealthEH’s medical and business standards, followed FDA rules on permissible health claims and labeling, and was manufactured in facilities adhering to Current Good Manufacturing Practices (CGMPs).
• Quality and safety: We prioritized manufacturers that follow strict safety and quality protocols. Most selections are third-party tested.
• Effective dose: The supplements listed contain at least 10^6 (1 million) CFUs per gram.
• Price: We included products across price ranges so you can find an option that fits your budget.
• Men’s needs: We favored formulas with strains and additional ingredients that specifically support men’s health.

Probiotic refresh

good, helpful bacteria

these microorganisms, or microbiomes, provide health benefits for your gut and beyond

food is your best bet

ideally, your diet should supply many probiotics

probiotic strains are not sex-specific

however, responses to supplements may differ by sex*

* Source on probiotic responses by sex.

How probiotics may benefit men

Certain probiotics might improve urinary tract and prostate health. A 2021 study of 20 men aged 55–65 with recurrent urinary infections found that those who took probiotics for 12 weeks had lower urinary loads of Escherichia coli (E. coli) and Enterococcus faecalis (E. faecalis) compared with a placebo group. These bacteria are common causes of urinary infections.

Research also shows probiotics may help reduce inflammation, which could benefit men with prostatitis.

Probiotics might also support male fertility. In one study, probiotic supplementation led to a meaningful increase in sperm concentration and motility. Nonetheless, more studies are necessary to clarify probiotics’ role in male fertility.

What to look for in a men’s probiotic

If you’re considering a probiotic supplement, pick safe, high-quality products that deliver proven strains at evidence-based doses. Different strains have distinct effects on gut and overall health.

If your goal is to target a particular condition, like IBS, consult a healthcare professional to identify a probiotic best matched to your needs, since specific strains and doses are more effective for certain symptoms and disorders.

Choose products that guarantee CFU counts through the expiration date so you can be confident you’re buying an effective supplement.

That said, probiotics aren’t necessary or suitable for everyone. They may be most helpful for people who eat few probiotic-rich foods. More research is needed on the benefits of probiotic supplements in healthy adults.

If you have severe or persistent side effects, stop taking the product and consult a healthcare professional.

Frequently asked questions about probiotics for men

Should a man take probiotics?

Probiotics can be a helpful way to support digestive health. Evidence suggests these supplements may reduce gut inflammation and offer prostate benefits.

Probiotics can be a helpful way to support digestive health. Evidence suggests these supplements may reduce gut inflammation and offer prostate benefits.

Do probiotics increase testosterone?

Current evidence doesn’t support probiotics as a way to raise testosterone lost with aging.

A recent study found that neither high- nor low-dose probiotics affected testosterone levels in men aged 50 to 65, although triglyceride levels fell significantly.

Current evidence doesn’t support probiotics as a way to raise testosterone lost with aging.

A recent study found that neither high- nor low-dose probiotics affected testosterone levels in men aged 50 to 65, although triglyceride levels fell significantly.

Do men need specific probiotics?

There’s no proof that men require different probiotic strains than women. However, many men-focused probiotics include multivitamins tailored to men’s needs.

There’s no proof that men require different probiotic strains than women. However, many men-focused probiotics include multivitamins tailored to men’s needs.

Takeaway

Probiotic supplements can offer men several health benefits, from easing symptoms of common digestive disorders to supporting prostate health and potentially aiding fertility.

While probiotics aren’t appropriate for everyone, some men may gain from a high-quality supplement tailored to their health goals.

If you have concerns about urinary, digestive, or metabolic health, consider discussing with your healthcare provider whether adding a probiotic supplement to your routine is a good option.