MSM is a naturally occurring substance that some people say may encourage hair growth. However, current research is insufficient to conclusively confirm these claims. Consult a healthcare provider before using MSM for hair-related concerns.
Methylsulfonylmethane (MSM) is a sulfur-containing compound present in plants, animals, and humans. It is also producible through chemical synthesis.
MSM is often highlighted for its anti-inflammatory effects. Because of this attribute, it’s commonly taken as an oral supplement to ease pain and swelling associated with various conditions, which can include:
- tendinitis
- osteoporosis
- muscle cramps
- headaches
- joint inflammation
It is also offered as a topical product intended to smooth wrinkles, reduce stretch marks, and help treat minor skin injuries.
In recent years, MSM has drawn interest for possible benefits related to hair growth.
MSM for hair growth
MSM is recognized as a sulfur-rich compound with anti-inflammatory activity. There is some preliminary, inconclusive research exploring its role in hair growth and retention. MSM’s sulfur content might help form bonds that strengthen keratin in hair and potentially influence hair development.
An earlier 2009 study investigated the effects of MSM combined with magnesium ascorbyl phosphate (MAP) on hair growth and alopecia in mice. Researchers applied different concentrations of MAP and MSM solutions to the animals’ backs. The findings suggested that hair growth varied depending on the amount of MSM used alongside MAP.

A 2019 trial with 63 human participants indicated that oral MSM supplements might enhance the look of hair and nails. In that study, participants taking a higher dose of 3 grams per day experienced faster and more noticeable effects compared with those taking 1 gram daily.
Researchers proposed that MSM could supply sulfur to keratin, helping to fortify bonds between keratin molecules. Still, the study disclosed some conflicts of interest, and additional research is necessary to verify MSM’s effectiveness for promoting hair growth.
Daily dosage
The Food and Drug Administration (FDA) lists MSM as Generally Recognized As Safe (GRAS) for its intended uses, according to the FDA GRAS database.
MSM supplements are sold in many health stores and pharmacies in tablet form. Toxicity research suggests MSM can be taken safely at higher daily amounts, commonly between 500 milligrams and 3 grams. MSM is also available as a powder to mix into hair conditioner.
Because MSM’s role in hair growth remains under study, the FDA does not provide an official recommended dose for that purpose.
Before adding MSM supplements to your regimen or changing your intake, review potential risks and dosing with your physician.
When choosing a product, consider brands verified by the United States Pharmacopeial Convention, which tests supplements to confirm their ingredients and quantities match label claims.
MSM-rich foods
You may already consume foods that naturally contain sulfur or MSM. Typical food sources include:
- coffee
- beer
- tea
- milk
- tomatoes
- alfalfa sprouts
- leafy green vegetables
- apples
- raspberries
- whole grains
Cooking can reduce the natural MSM content of these foods. Eating MSM-containing items raw or minimally processed preserves higher amounts of the compound. MSM supplements can be used alongside naturally occurring MSM in the diet.
Side effects of MSM for hair growth
A 2017 review reports minimal to no adverse effects from MSM supplementation.
Possible side effects, if they occur, are generally mild and may include:
- headaches
- nausea
- abdominal discomfort
- bloating
- diarrhea
Discuss potential side effects and interactions with any medications or supplements you are taking with your healthcare provider.
Because research on MSM safety during pregnancy and breastfeeding is limited, avoid MSM supplements if you are pregnant or nursing unless advised otherwise by a doctor.
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The bottom line
MSM is a sulfur-containing compound naturally found in the body and sometimes used to address osteoporosis and joint inflammation. Some people believe it can help with hair loss, but there is not yet enough evidence to confirm that MSM supplements promote hair growth.
If you want to encourage hair growth or address hair loss, consider established treatments with stronger research support.
If you’re uncertain about the best approach for supporting hair health, consult a healthcare professional to review your options.


















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