Acne vulgaris is a chronic inflammatory condition of the pilosebaceous unit, affecting adolescents and adults alike. This category covers the pathophysiology of comedonal, papulopustular, nodulocystic, and hormonal acne subtypes. Articles address first-line topical therapies such as retinoids and benzoyl peroxide, systemic options including oral antibiotics and isotretinoin, and adjunctive procedures like chemical peels. Clinical precautions regarding antibiotic resistance, teratogenic risk with isotretinoin, and the role of diet and stress in lesion propagation are also examined to support informed, dermatologist-guided management.