Zynlonta Cost Assistance: How to Save on Treatment

If you’ve landed on this page, chances are you (or someone you love) is looking at Zynlonta and wondering, “How much will this actually cost me?” You’re not alone. The price tag for a single 10 mg IV dose can feel like a mountain—about $29,651 according to Drugs.com. But the good news? There are ways to bring that number way down, sometimes to $0 per dose.

Quick Start Summary

Here’s the TL;DR you need right now:

• Price reality: Cash‑pay price averages $29,651 per 10 mg injection.
• Zero‑copay option: If you have private/commercial insurance, you may qualify for a $0‑copay program worth up to $25,000 per calendar year (see the ADVANCING Patient Support Copay Assistance Program).
• Next step: Call 855‑690‑0340 or start the online enrollment to see if you qualify.

That’s it—no need to scroll through dense pages or wait for a second opinion to understand the basics. Below we’ll unpack each piece, walk you through the paperwork, and share a few real‑world stories so you feel confident about the path ahead.

Understanding Zynlonta Pricing

What is the list price for Zynlonta?

The “list price” is what you’d pay if you walked into a pharmacy with a cash check and no insurance. According to Drugs.com, a single 10 mg intravenous injection sits at roughly $29,651. That figure can wiggle a bit—pharmacy location, stock shortages, and whether you’re buying a single dose or a multi‑dose pack all play a role.

How do insurance plans affect the out‑of‑pocket cost?

Most patients don’t pay that full amount because insurance steps in. Here’s a quick breakdown:

• Deductible: The amount you pay before insurance starts helping. If your plan’s deductible is $2,000, that’s your first chunk.
• Coinsurance: A percentage of the drug’s price after the deductible—often 20% for specialty drugs. Twenty percent of $29,651 is about $5,930.
• Copay: Some plans set a flat copay per infusion (e.g., $100), but many use coinsurance instead.

Put together, a typical patient with a $2,000 deductible and 20% coinsurance might see an out‑of‑pocket bill of roughly $7,930 for the first infusion. Subsequent doses could be lower once the deductible is met.

Price Comparison Table

Setting	Approx. Cost per 10 mg	Typical Patient Cost*
Cash‑pay (no aid)	$29,651	$29,651
Commercial insurance + copay card	$29,651	$0‑$6,000 (depends on deductible/coinsurance)
ADVANCING copay assistance	$29,651	$0 (up to $25K/yr)

*These numbers assume a standard private plan; individual experiences will vary.

Eligibility for Assistance

Commercial/Private Insurance Eligibility

The most generous assistance—$0 per dose—requires a few straightforward conditions:

• You’re 18 years of age or older.
• You have a private/commercial prescription drug plan (employer‑based, marketplace, or self‑pay).
• You live in the United States or its territories.
• You have a valid Zynlonta prescription for an FDA‑approved indication.
• You’re not covered by Medicare, Medicaid, TRICARE, VA, or any other government‑funded program.

If any of those don’t line up, don’t panic—there are still options.

Patient Assistance Programs for Low‑Income or Uninsured Patients

Charitable foundations such as the HealthWell Foundation and the Patient Access Network (PAN) often provide full‑cost coverage for patients who lack commercial insurance or whose income falls below a set threshold. The application typically asks for recent tax returns, proof of residence, and a doctor’s letter confirming the medical need.

While the paperwork can feel a bit daunting, most hospital social workers or the Zynlonta dedicated case managers will walk you through every step. They’re basically the “friend you wish you had” in the middle of a bureaucratic maze.

Eligibility Checklist

• ✅ Age ≥ 18
• ✅ Private/commercial insurance (for $0 copay program)
• ✅ Valid Zynlonta prescription
• ✅ No concurrent Medicare/Medicaid coverage
• ✅ Ability to submit an Explanation of Benefits (EOB) within 180 days (for copay assistance)

Enroll in Copay Program

Step‑by‑Step Enrollment Process

Getting the $0‑copay program up and running is simpler than you might think. Follow these four steps:

1. Call the helpline. Dial 855‑690‑0340 or head to the ADVANCING website. A friendly case manager will verify your insurance details.
2. Provide prescription info. Your oncologist’s office will need to share the Zynlonta order and the dosing schedule.
3. Submit the latest Explanation of Benefits (EOB). This is the statement your insurer sends after a claim is processed. It must show the out‑of‑pocket amount you’d otherwise owe. The submission window is 180 days from the infusion date.
4. Receive confirmation. Within a week you’ll get a copay‑reduction card that you present at the infusion center. The pharmacy/system will apply the $0 cost automatically.

Required Documents & Common Pitfalls

Here’s what you’ll need on hand:

• Copy of your insurance card (front and back).
• Most recent EOB (or a copy of the claim if you haven’t received the EOB yet).
• Proof of residence (utility bill, driver’s license).
• Doctor’s written prescription for Zynlonta.

Common bumps include:

• Late EOB submission. Miss the 180‑day window and you’ll lose the copay benefit for that dose.
• Missing insurance info. A typo in your member ID can cause a denial—double‑check before sending.
• In‑eligible insurance. If your plan is flagged as Medicare/Medicaid, the program will automatically reject the request. In that case, pivot to a charitable PAP.

Sample Email to Your Oncology Office

Feel free to copy this short note when you ask your clinic to start the enrollment:

Subject: Request to Initiate ADVANCING Zynlonta Copay AssistanceHi [Oncologist's Name],I hope you're doing well. I'd like to enroll in the ADVANCING Patient Support copay assistance program for my upcoming Zynlonta treatment. Could you please send my prescription details and the latest EOB to the program's case manager? Their contact is 855‑690‑0340.Thank you for your help!Best,[Your Name]

Prior Authorization Tips

Why Zynlonta Often Needs Prior Authorization

Zynlonta is a high‑cost, specialty oncology drug. Insurers demand proof that you meet the FDA‑approved criteria (relapsed or refractory diffuse large B‑cell lymphoma after at least two prior regimens). That’s where the prior‑auth comes in: it protects the payer from paying for a therapy that might not be medically necessary.

Who Handles the Prior‑Auth Paperwork?

Good news—when you’re enrolled in ADVANCING, a dedicated case manager can submit the prior‑auth on your behalf. They’ll gather the diagnosis code (ICD‑10 C83.3), treatment history, and any required pathology reports. Their goal is to get the authorization “in the green” within 5‑10 business days.

Prior‑Auth Checklist

• Diagnosis code (C83.3 – Diffuse Large B‑Cell Lymphoma)
• Documentation of ≥ 2 prior therapy lines
• Most recent pathology/histology report
• Valid Zynlonta prescription
• Insurance policy number and member ID

Having these items ready dramatically speeds up the process and reduces the chance of a frustrating back‑and‑forth with your insurer.

Additional Savings Tools

Drugs.com Discount Card

The free Drugs.com Discount Card can shave up to 80 % off the cash price at over 65,000 pharmacies nationwide. It works like a coupon—just print it, present it at the pharmacy, and watch the price drop. Remember, this card only applies to cash‑pay patients; it can’t be stacked with insurance‑based copay programs.

Manufacturer‑Provided Copay Cards & Rebates

ADC Therapeutics (the makers of Zynlonta) runs the ADVANCING Patient Support program, which we covered earlier. The program’s terms state that eligible patients may pay $0 per dose up to a $25,000 annual cap. If you qualify, you’ll get a physical card that looks like a credit card—hand it to the infusion center staff, and they’ll apply the benefit instantly.

Comparison of Savings Options

• ADVANCING Copay Assistance – $0 per dose, up to $25K/yr, requires private insurance.
• Drugs.com Discount Card – Up to 80% off cash price, works at most retail pharmacies.
• Charitable PAPs (HealthWell, PAN) – May cover 100% of cost for low‑income or uninsured patients.

Real World Experience

Patient Story: “Maria’s $20,000 Savings”

Maria, a 58‑year‑old teacher from Ohio, was diagnosed with relapsed DLBCL in early 2024. Her oncologist recommended Zynlonta, but the cash price left her eyes wide. After a quick call to the ADVANCING helpline, she learned she qualified for the $0‑copay program. Within two weeks, the case manager secured enrollment, submitted her EOB, and Maria received her first infusion with no out‑of‑pocket bill. By the end of her first year, she had saved roughly $20,000 compared to what a cash‑pay patient would have paid.

Oncologist’s Perspective

Dr. Lisa Nguyen, a board‑certified hematology‑oncology specialist, says, “When we present Zynlonta, the first question is always cost. I make it a point to connect patients with the ADVANCING case manager during the initial consult. It not only eases their financial worries but also speeds up prior‑authorization because the case manager knows exactly what the insurer wants.”

Lesson Box

Ask your doctor about the copay program at the first appointment. Early engagement = fewer delays and less stress.

Conclusion

Facing a high‑cost therapy like Zynlonta can feel overwhelming, but you don’t have to navigate it alone. By understanding the list price, leveraging insurance benefits, and tapping into the ADVANCING Copay Assistance Program, you could walk into your infusion center with a $0 bill for each dose. If you lack private insurance, charitable patient assistance programs stand ready to step in.

Take the next step today: call 855‑690‑0340, grab the free discount card from Drugs.com, and ask your oncology team to start the prior‑auth paperwork. You deserve the best treatment without the financial headache, and we’re cheering you on every step of the way.

Got questions or want to share how you saved on Zynlonta? Drop a comment below—your experience could be the lifeline another reader needs.