4 Best DHT-Blocking Shampoos

A quick look at the best DHT-blocking shampoos

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Certain shampoos and treatments are crafted to inhibit dihydrotestosterone (DHT), a sex hormone that contributes to hair thinning. These DHT inhibitors might help slow hair loss. We examined (pun intended) dozens of shampoos to identify the top choices available.

Continue reading for our picks and to learn more about DHT.

Healthline’s picks for the best DHT-blocking shampoos

Comparison of the best DHT-blocking shampoos

ProductPriceKey ingredientsPrescription needed?

$19saw palmettono

$24 for one-time purchase; $8/month subscriptionsaw palmetto and caffeineno

$72 for one-time purchase; $55/month subscriptionbiotin, saw palmettono

$12.95biotinno

How we chose the best DHT-blocking shampoos

Although many products claim to block DHT, not all have solid research to back them up.

We prioritized products from trusted brands that include DHT-inhibiting ingredients with the strongest research support, such as:

• Saw palmetto: Saw palmetto is derived from the berries of a palm native to the southeastern United States. Shampoos formulated with saw palmetto to thicken hair may help reduce DHT levels, clear clogged follicles, and promote regrowth. More research is needed, but a of existing studies found it can provide modest improvements in hair regrowth.
• Finasteride and minoxidil: Finasteride is the generic equivalent of Propecia, a prescription medication for male-pattern hair loss. Minoxidil is the generic form of Rogaine, a widely used topical option targeting the crown. has shown these agents can slow the progression of male pattern baldness, though they typically offer only partial regrowth.
• Ketoconazole: Ketoconazole is best known for antifungal and anti-inflammatory benefits, which is why it’s commonly used to treat infections and conditions like seborrheic dermatitis. A including two animal studies and five human trials found ketoconazole may be a viable option for androgenetic alopecia.
• Pumpkin seed oil: Pumpkin seed oil is a natural oil that may support hair growth by preventing testosterone from converting into DHT. A reported men who took 400 milligrams (mg) of pumpkin seed oil daily for 24 weeks experienced a 40% increase in hair growth.

We also highlighted some products containing possible DHT inhibitors, such as certain essential oils. While these have less robust research, they could still be beneficial.

Finally, we reviewed customer feedback and included only products that mostly received positive ratings from buyers.

How does DHT cause hair loss?

Androgenetic alopecia — commonly called male pattern baldness — is a frequent cause of hair loss in men.

Although it can affect other genders, it’s less prevalent. About 50 million men in the United States have this condition, compared with 30 million women.

Testosterone is converted into DHT by an enzyme called 5-alpha reductase (5-AR). Once it’s in circulation, DHT can bind to receptors on hair follicles in the scalp, causing them to shrink.

that this may result in:

• less dense hair
• reduced regrowth
• a generally thinner-looking head of hair

What to look for in a DHT-blocking shampoo

You’ll see the following ingredients in many of our selections. These have the strongest evidence as DHT inhibitors:

• saw palmetto
• finasteride and minoxidil
• ketoconazole
• pumpkin seed oil

Other ingredients with less research include:

• green tea extract
• tea tree oil
• rosemary extract

Aside from DHT-blocking actives, look for strengthening agents like biotin and keratin, and hydrating oils such as coconut and argan oil.

If your hair is dry or curly, consider a shampoo free of sulfates, as they can be drying.

Is it safe to use a DHT-blocking shampoo?

DHT-blocking shampoos are generally regarded as safe.

However, if you have sensitivities or allergies, do a patch test before applying the product to your entire scalp. Apply a small amount of shampoo to the inside of your wrist and wait 24 hours to check for irritation.

Remember that even “natural” ingredients can cause allergic reactions or irritation.

It’s also wise to choose formulas without harsh chemicals and that are free from sulfates and parabens.

When to talk with a doctor

Hair loss is common with aging, but many other factors can contribute. Stress, hormonal changes, illness, infections, and medications may all lead to thinning hair. Talk to a medical professional if you’re concerned.

If your hair loss is sudden, patchy, or includes body hair loss, it might indicate an underlying medical issue that requires diagnosis and treatment.

Also consult a doctor if your hair loss is accompanied by symptoms such as itching, burning, or pain.

Hair loss can be a side effect of certain drugs. If you’re taking medications or recently started a treatment, ask your doctor or pharmacist whether hair loss is a known side effect.

Because stress and anxiety can contribute to hair loss, speak with a healthcare provider if you’re struggling with mental health. They can rule out medical causes and refer you to counseling or therapy to help manage symptoms.

In most instances, hair loss isn’t a sign of a serious illness. Still, consult a doctor if you’re worried—particularly if it affects your quality of life or comes with other symptoms. They can identify the cause and suggest treatment options.

Frequently asked questions about DHT-blocking shampoos

Does DHT-blocking shampoo actually work?

DHT is believed to drive follicle miniaturization and reduced hair density and quality, leading to male pattern baldness.

If this is the cause of your hair loss, regular use of a DHT-blocking shampoo may help improve the appearance of thinning hair.

It’s best to begin using such a product as early as possible. However, it can take months to up to a year to see full results.

Combining a DHT-blocking shampoo with a prescription hair-loss regimen may be beneficial if your doctor recommends it.

If your hair loss stems from causes other than DHT, these shampoos may not be effective.

How long does it take to see results from DHT-blocking shampoos?

Expect several months of consistent use, possibly alongside prescription treatments, before seeing noticeable changes.

What can you do to prevent hair loss?

People dealing with male pattern baldness can discuss preventive options with their doctors, including:

• minoxidil (Rogaine)
• finasteride (Propecia, Proscar)
• follicular unit transplantation (a hair transplant including underlying tissue)
• follicular unit extraction (a hair transplant harvesting only follicles without surrounding tissue)

Other at-home strategies include:

• trying scalp massage, which may promote hair growth
• using essential oils believed to support growth, like peppermint, Chinese hibiscus, ginseng, and jatamansi
• choosing a soft brush made of natural fibers

Low-level light therapy has also been shown to encourage cellular growth and repair.

Also avoid practices that can damage hair, such as:

• excessive heat styling
• chemical treatments or bleaching
• using harsh shampoos that can strip natural oils
• wearing tight hairstyles that pull on the hair

What are the side effects of DHT blockers?

Potential side effects from DHT inhibitors include:

• erectile dysfunction
• ejaculatory difficulties, such as premature or delayed ejaculation
• development of breast enlargement and tenderness
• rash
• nausea and vomiting
• congestive heart failure from fluid or salt retention

Takeaway

DHT is a sex hormone linked to male traits and a common contributor to hair loss. Shampoos that aim to block DHT may help improve thinning hair.

Always perform a patch test before trying a new product.

Talk with your doctor about whether a hair-loss treatment plan should be used alongside a DHT-blocking shampoo.