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  • Tepezza is a prescription medication used to ease symptoms of thyroid eye disease (TED) in adults.
  • The cost of Tepezza can differ depending on your insurance, treatment regimen, and the pharmacy or infusion site you use.
  • There may be a patient assistance option called Amgen By Your Side to help offset Tepezza expenses.
  • Tepezza (teprotumumab-trbw) is supplied as a powder that’s reconstituted into a liquid and administered as an intravenous (IV) infusion (an injection into a vein delivered over time). Most people receive their Tepezza doses in a physician’s office, hospital setting, or an infusion center.

    The image depicts a close-up view of a person's arm with an IV line inserted, illustrating an infusion treatment.
    (img by Kherkher Garcia)
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    What’s the price of Tepezza?

    The cost of Tepezza varies. What you pay will be influenced by your treatment course, whether you have insurance and what it covers, and the pharmacy or infusion facility involved. Your out-of-pocket expenses will also include charges for the office or clinic visits needed to get the infusions.

    To determine your expected cost for Tepezza, speak with your doctor or your insurance company.

    FAQ about cost and Tepezza

    Below are answers to frequently asked questions about Tepezza and its cost.

    What’s Tepezza’s cost per month?

    Tepezza isn’t taken monthly. The usual complete Tepezza regimen for TED includes eight IV infusions given over roughly 5 months. Your overall expense will hinge on several things, such as:

    • whether you’re eligible for and enroll in a savings program
    • the number of Tepezza infusions you receive
    • your individualized treatment plan
    • the extent of your insurance coverage

    Talk with your physician or pharmacist to estimate how much Tepezza might cost you. If you have insurance, contact your insurer to learn whether Tepezza is covered and to what degree.

    How much does Tepezza cost if I have Medicare?

    To learn whether your Medicare plan will cover Tepezza, call your plan administrator. Medicare plans vary widely, and coverage and costs differ according to the specific benefits of your plan.

    Your final expense may also reflect the fee for receiving Tepezza at a clinic or doctor’s office.

    You can also ask your prescribing clinician about likely costs if you’re on Medicare.

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    Can I get help paying for Tepezza?

    If you require assistance paying for Tepezza or understanding your insurance options, consider these resources:

    These sites provide information about insurance, drug assistance programs, and links to savings cards and other cost-saving services. For personalized guidance on covering your prescription costs, discuss options with your doctor or pharmacist. You may also find information about tepezcohuite relevant on related resource pages.

    Is Tepezza available as a generic or biosimilar?

    Tepezza is currently only available as a brand-name biologic; there is no biosimilar or generic version at this time.

    Note: Conventional (small-molecule) drugs are synthesized chemically and can have generics that are exact copies of the brand product. Biologics, by contrast, are produced from living cells and cannot be duplicated exactly, so they have biosimilars rather than generics. Like generics, biosimilars are deemed to be as safe and effective as the original biologic but often cost less.

    Why is there such a cost difference between biologic drugs and biosimilar drugs?Biologic medications often carry high prices because of the extensive research, development, and testing needed to establish safety and efficacy. The original biologic manufacturer can market the drug exclusively for up to 12 years. After patent protections end, other companies may introduce biosimilar versions. Competition can drive down prices, and because biosimilars are highly similar to the original biologic, they don’t require the same breadth of clinical studies—factors that can reduce their cost.

    Disclaimer: Every effort has been made to ensure the information in this article is accurate, complete, and current. However, it should not replace the advice and expertise of a licensed healthcare professional. Always consult your physician or another qualified healthcare provider before starting any medication. Drug information can change and does not encompass every possible use, direction, precaution, warning, drug interaction, allergic reaction, or adverse effect. The lack of specific warnings or other information for a given drug does not mean that the drug or combination is safe, effective, or appropriate for every patient or every use.

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    Frequently Asked Questions

    What is the typical Tepezza treatment schedule?

    How much does Tepezza usually cost out of pocket?

    Will Medicare cover Tepezza?

    Are there programs to help pay for Tepezza?

    Is there a generic version of Tepezza?

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    Disclaimer: This article is for informational purposes only and is not intended as medical advice. Please consult a healthcare professional for any health concerns.

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