The body is continually undergoing change. Specifically, the cells that make up your skin are in a constant state of renewal.
Your skin accomplishes this through ongoing regeneration and repair mechanisms.
At the microscopic level, skin cells are continually sloughing off, uncovering fresh, newly formed cells beneath. This is one reason scars and blemishes can slowly become less noticeable over time.
Grasping the biology behind your skin’s lifecycle can help you care for it while it regenerates. It can also guide you in enhancing the skin’s natural renewal process to achieve a revitalized radiance.
Here’s advice from skin care professionals on ways to accelerate skin regeneration.
What is skin regeneration?
According to 2015 research, skin regeneration describes the full replacement of damaged tissue with new tissue. Skin repair, by contrast, refers to the ongoing healing of existing tissue. Regeneration is generally not linked with scar tissue.
The study explains that skin regeneration can occur via two pathways:
- restoration — piecing together what’s been broken
- reconstruction — replacing and rebuilding what’s been lost
Skin regeneration is a natural biological process happening at the cellular level.
“Epidermal cells, or the top layers of the skin, are in a perpetual cycle of replacement,” says Laura Chacon-Garbato, a licensed esthetician and director of education at Herbalife. “This renewal involves shedding the epidermis.”
Put simply, skin regeneration is a continual turnover of cells.
According to a , the epidermis is sustained by stem cells situated in the skin’s deepest layer. These epidermal stem cells generate progeny that migrate upward toward the skin’s surface.
During that ascent, cells that produce keratin undergo a series of biochemical and structural transformations that form the distinct layers of the skin.
“This process lends the skin a youthful, healthy sheen,” adds Jennifer Hurtikant, chief science officer at Prime Matter Labs.

The skin regeneration process
The same estimated that epidermal turnover happens on average every 40 to 56 days.
“When we’re young, exfoliation occurs naturally, but as we age this rhythm changes and slows,” Chacon-Garbato explains.
An earlier 2006 study notes that the typical 28-day skin turnover extends by roughly 30 to 50 percent by age 80.
For people older than 50, Chacon-Garbato says, the cycle can stretch to as long as 84 days.
“This slowdown leads to buildup and an excess of dead cells that can make the skin appear fatigued, dull, and lackluster,” she says.
Throughout this cycle, several cellular events take place.
First, new cells form deep within the epidermis.
Then, as those skin cells mature and eventually die at the epidermis’s surface, they naturally slough off.
The skin healing process
A cut or burn can leave a scar.
That happens because fibroblasts in scar tissue lay down collagen in a different pattern than in normal skin, producing tissue that’s thicker and less flexible.
Still, by enhancing skin regeneration, scars can gradually diminish as new, healthy skin grows beneath them.
How to boost skin regeneration
With age, the rate of skin regeneration decreases, leaving a layer of dead cells on the skin’s surface.
Supporting the natural renewal process helps skin stay refreshed and elastic, even as you grow older.
Lifestyle choices
Healthy habits support optimal skin regeneration.
Hurtikant recommends:
- consistent physical activity
- a nutrient-rich diet
- adequate hydration
- managing stress where possible
- shielding from environmental aggressors like UV radiation, pollution, and dry conditions
There are two categories of aging: intrinsic (cellular) aging and extrinsic (environmental) aging.
Intrinsic aging is a genetically driven, natural process that can be exacerbated by stress. Extrinsic aging results from external influences, such as locale and lifestyle choices.
“Stress drives intrinsic aging and the environment drives extrinsic aging,” Hurtikant notes.
Chacon-Garbato advises prioritizing protein-rich foods such as:
- nuts and seeds
- legumes
- fish
- poultry
“Proteins are crucial for tissue repair and building new tissue,” she explains. “Cells require protein to sustain themselves, so the body uses dietary protein to replace worn-out or dead skin cells.”
Also choose foods high in antioxidants, like:
- blueberries
- strawberries
- apples
- ginger
- turmeric
Adding antioxidants to your meals may enhance the skin’s radiance and sheen.
Products
Certain skincare formulas can aid natural cell turnover, hydrate the skin, and clear away accumulated dead cells. Seek ingredients such as:
- vitamin B3 (niacinamide)
- vitamin C
- vitamin E
- alpha-lipoic acid (ALA)
- hyaluronic acid
“Use products with vitamin B3,” Chacon-Garbato recommends. It’s “a vital piece of cell metabolism, known as niacinamide, and is required for numerous skin functions that help preserve a healthy-looking complexion.”
She also advises incorporating antioxidants like vitamins C and E to guard cells against free radical damage.
Consider Swisse Beauty Skin Regeneration+, an oral supplement containing ALA, and Musely FaceRx Anti-Aging Night Cream featuring tretinoin, hyaluronic acid, and niacinamide.
Natural remedies
These natural options may support skin health and the regeneration process:
- papaya extract
- jojoba oil
- rosehip oil
- coconut oil
- citrus extracts, such as orange peel
A 2022 study identified several plant extracts, including papaya, with antioxidant and antiwrinkle benefits. Extracts using ethanol as a cosolvent demonstrated stronger effects.
A found that jojoba, rosehip, and coconut oil can aid skin barrier restoration, wound recovery, antioxidant activity, and antiaging effects.
A observed that orange peel extract might offer protection against, or relief from, UV-induced damage.
You can search for natural skincare items that include these components.
Citrus can increase photosensitivity, or sensitivity to light. Use caution when applying citrus in any form to the skin by avoiding direct sun exposure and using sun protection. Never apply citrus oils directly to the skin.
Procedures
If you want a deeper exfoliation, a dermatologist can provide more intensive skin resurfacing treatments to jump-start rejuvenation. Be sure your dermatologist is board certified.
Chacon-Garbato recommends:
- laser skin resurfacing
- microdermabrasion
- chemical peels
- microneedling
“There’s no universal solution for every skin type, so consult your dermatologist to determine the ideal approach for the results you want,” she advises.
Frequently asked questions
Curious for more? See the FAQs below.
Does aloe vera help with skin regeneration?
Aloe vera promotes cellular diversity and helps keep skin well hydrated and protected.
According to a , it also offers innate antioxidant and anti-inflammatory properties.
“Aloe vera is an excellent daily ingredient because of its restorative and soothing attributes,” Chacon-Garbato says. “It’s also a highly effective hydrator and helps reduce skin dryness.”
She mentions that aloe has been used for generations for beauty because it delivers moisture directly to tissue and helps prevent water loss through evaporation.
Hurtikant notes that while aloe vera is beneficial for regeneration, other trending ingredients include algae and mushroom derivatives, as well as hyaluronic acid.
What’s the best cream for skin regeneration?
Many skincare formulations have been shown to improve the visible signs of aging by accelerating the skin’s natural renewal.
One well-reviewed option is Musely FaceRx Anti-Aging Night Cream, which contains active components like tretinoin (Retin-A), niacinamide, and hyaluronic acid.
These ingredients are effective at promoting exfoliation, so check for them when selecting creams to encourage regeneration.
How long does it take for your skin to regenerate?
For most adults under 50, the cycle ranges from about 28 to 42 days. For those over 50, it can extend up to 84 days, though this varies.
The duration of your skin’s regeneration cycle depends on several factors, including:
- age
- diet
- skincare routine
- hydration
- environmental exposures
How do you speed up skin regeneration?
There are multiple ways to enhance skin renewal.
Simple lifestyle adjustments like regular exercise and better hydration help keep the process functioning effectively.
Skincare products with exfoliating ingredients can also remove excess dead cells.
Certain procedures can stimulate faster formation of new skin cells and hasten regeneration.
Does aging skin still regenerate?
Aging slows the regeneration process, but it never stops entirely.
Because renewal becomes much slower over time, skin can look thicker, less supple, and more wrinkled or textured.
This happens because reduced turnover leaves more dead cells lingering on the surface.
Takeaway
Skin regeneration is a natural cycle in which epidermal cells turnover: dead cells on the top layer slough off, revealing fresh cells beneath.
By supporting this cycle through healthy living and a consistent skincare routine, you can maintain a vibrant glow as you age.
Keep in mind: while you can encourage skin regeneration, the cycle naturally slows with age. A few lines and some texture are normal and nothing to be ashamed of.
You might even view them as markers of life experience and wisdom.


















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